Glovebox ventilation design must be carefully performed and reviewed to ensure that during both design conditions, as well as upset conditions, the glovebox ventilation system continues to operate in a safe manner to ensure that workers and the surrounding confinement area do not become contaminated.
Following is a summary of how to determine the design requirements (operating pressure and flowrate) for a glovebox as well as the local filter, instrumentation, and controls for a typical glovebox.