Biotech laboratory facilities consume up to 10 times more energy than commercial facilities. This is partly because lab buildings require 100% outside air at high volumetric flow rates for safety reasons that are mandated by regulations, codes, and standards. The National Institute of Health (NIH) states, "Laboratory buildings should be designed with ‘once-through' 100% outdoor air systems that automatically compensate for filter loading. Laboratory air shall not be recirculated."
To give you a visual perspective on the volume of air that a typical laboratory uses, I would like to compare it to something tangible such as the volume of a zeppelin like the Hindenburg, which was over 800-ft long and over 7 million cu ft in volume.