successful design and realization of a validatable life sciences
cleanroom won’t happen by chance. Early and continuous
coordination and communication among all parties involved - from
process design and scale-up through cGMP layout, pre-construction
design review, commissioning, validation, and onsite inspection by
regulatory authorities - is essential. The time spent in design
optimization in the front end, well in advance of the “bricks and
mortar” stage, will be saved many times over.
Leaning on experience and data from various K-12 cities and projects, the author pursues some less conventional design approaches. They may revolve around radiant heating and/or cooling, but depending on school size and other factors, the smart use of heat recovery, DOAS, and improved central plants could also put a project on the HVAC honor roll.